Source of ligands, such as PD-L1, which inhibit the anti-tumor response through interaction with receptors present on T cells [79]Transport of soluble factors, such as Fas and TRAIL, which induce Teff cell apoptosis [80]Exosomes with high IL-6 content can inhibit monocyte differentiation into DCs [81]. The gene discussed is CD274; the disease is neoplasm.