Other miRNAs, such as miRs -16-5p, -17-5p, and -20a-5p, were present in greater amounts in the sera of melanoma patients who responded positively to anti-PD-1 therapy in comparison to those who were resistant to this form of treatment, which may suggest that these miRNAs can be utilized as indicators of therapeutic efficiency [136]. Here, PDCD1 is linked to melanoma.