Considering the role of LPA1 in diverse experimental models, BMS might also be an effective therapeutic to treat other types of LPA1-associated diseases including cancer, lung injury, systemic sclerosis, neuropathic pain, spinal cord injury, hydrocephalus, hypoxia, neuropsychiatric disorders, and traumatic brain injury [12,13,14,15,16,17,18]. Here, LPAR1 is linked to systemic sclerosis.