Related to AD disease diagnosis, non-Aβ-Tau biomarkers including ApoE protein [66], ApoE-encoding gene [67,68], AD-related DNA [69,70], microRNA [71], α-1 antitrypsin [72], β-secretase [73], and immunoglobulin [74], have been successfully detected electrochemically using various nanomaterial-based sensing strategies. Here, APOE is linked to Alzheimer disease.