Using Pearson's correlation coefficient and linear regression, significant inverse correlation (r = -0.3, p = 0.1, and r = -0.32, p = 0.03) between the expression of SRRM2 and miR-27b-3p was revealed not only among the PD patients but also between PD patients and healthy subjects respectively (Fig 5A and 5D). The gene discussed is SRRM2; the disease is Parkinson disease.