APLN and Cirrhosis: However, both peptides, like apelin, are significantly reduced in patients with cirrhosis (BMP9, 218.1±9.5 vs 124.9±15.7 pg/ml, p<0.002; pBMP10, 3479.6 ± 298.3 vs 1236.1 ± 184.6 pg/ml, p < 0.0001).