Also noted were that the variance among sample replicates was greater for the 2N4R vs. 2N3R substrate, and that some tauopathy brain samples, e.g. AD3, AD9, and PSP1, were not significantly different (p > 0.05) from the no-disease brains (Figures 2(b) and 3(b)). The gene discussed is PSPC1; the disease is tauopathy.