In the TCGA training set, breast cancer samples including 105 samples of Basal subtypes, 42 samples of Her2-enriched subtypes, and 175 samples of Luminal A subtypes and 204 samples of Luminal B subtypes, were divided into different molecular subtypes according to the pam50 method (S6 Table) into the high- and low-risk groups. The gene discussed is ERBB2; the disease is breast carcinoma.