TAS2R38 and cardiovascular disorder: As an example that concerns TAS2R38, the frequency of vegetable and fat intake, is reciprocally regulated by the functional haplotype PAV, i.e., an increased intake of vegetables and decreased intake of fat [26], so favouring the intake of anti-inflammatory foods [27], known to confer protection against inflammatory age-related diseases [25], including cardiovascular disease ones, the most important death cause in the Western World [3].