LMNA and laminopathy: Despite mutations in LMNA have been associated with a heterogeneous group of diseases, known as the “laminopathies,” four main clinical phenotypes affecting skeletal and cardiac muscle have been reported including limb-girdle muscular dystrophy type 1B (LGMD1B), the Emery-Dreifuss muscular dystrophy (EDMD), congenital muscular dystrophy (MDCL), and dilated cardiomyopathy [25, 26].