In the primary human colon cancer cells that were derived from two other colon cancer patients, pri-Can-2 and pri-Can-3, transfection of si-Lnc-EPIC1-s1 or si-Lnc-EPIC1-s2 resulted in over 90% reduction of Lnc-EPIC1 expression (Figure 2H). This evidence concerns the gene EPIC1 and malignant colon neoplasm.