MAPK3 and nasopharyngeal carcinoma: Although we detected a decrease in MAPK3 gene expression in all the 16p11.2 deletion lines [Figure 5—figure supplement 1A], we did not observe any changes in NPC proliferation between wild type and deletion lines indicating that MAPK3 may not influence NPC proliferation in these 16p11.2 patient lines [Figure 4—figure supplement 2A].