The AUCs for miR‐1307‐3p, piR‐019308, piR‐004918 and piR‐018569 for discriminating GC patients from healthy controls were 0.845, 0.820, 0.754 and 0.732, respectively, which are markedly greater than that of CEA, CA199 and AFP. This evidence concerns the gene AFP and gastric cancer.