CDKN1A and cervical squamous intraepithelial neoplasia: Along this line, it was shown that 50% of CRC cases show a loss of CDKN1A expression and this correlated with CIN, but not with MIN/MSI [52], which is in agreement with our results from colorectal and breast cancer showing that loss of CDKN1A correlates with the CIN status of the cancer samples.