CDK1 and cervical squamous intraepithelial neoplasia: It is of note that we were not able to consistently associate alterations in p53, p73, p21CIP1 or CDK1 protein levels with increased microtubule polymerization rates in the different W-CIN cell lines (Fig. S9) suggesting that various mechanisms and alterations might contribute to CDK1 deregulation in human cancer cells (see model in Fig. 7).