NEAT1 and neoplasm: To further examine the relationship between c-Myc or ALDH1 expression and NEAT1 in clinical samples, we performed immunohistochemistry (IHC) staining to measure c-Myc and ALDH1 in tissue specimens of cohort B. ALDH1 and c-Myc exhibited higher expression in NEAT1 high expression tumor tissue specimens compared to the low NEAT1 expression tissues (Fig. 7A).