We next selected the 2 oleacein mimetics with the best CSC-targeted profile (i.e., anti-CSC activity at low micromolar range and lack of cytotoxic activity against differentiated cancer cells), namely CHEMBL1950046 (3,4-dihydroxyphenethyl butyrate; a.k.a. hydroxytyrosol butyrate) and CHEMBL1632504 ((E)-N-allyl-2-((5-nitrofuran-2-yl)methylene)hydrazinecarbothioamide), to evaluate their capacity to target epithelial-like CSC cells with high levels of ALDH1 (ALDH1+). The gene discussed is ALDH1A1; the disease is cancer.