We then confirmed by qPCR that LINC00452 was also significantly upregulated in all general ovarian cancer cell lines including OVCAR3, SKOV3, CaOV3, A2780 and HO-8910 cells in comparison to the normal ovarian epithelial cells IOSE80 with the highest abundance detected in CaOV3 cells (Supplementary Figure 1). This evidence concerns the gene LINC00452 and ovarian carcinoma.