Notably, a pathological study on postmortem spinal cord tissue has previously shown that α-synuclein is deposited at this region in individuals with α-synucleinopathies, including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, where it has been suggested to contribute to impaired micturition and/or constipation (34). This evidence concerns the gene SNCA and Lewy body dementia.