NFE2L2 and dry age related macular degeneration: In the RPE of a Nuclear factor erythroid 2-related factor 2 (NFE2L2/NRF2) and peroxisome proliferator-activated receptor-gamma captivator 1-alpha (PGC-1α) double knockout (dKO) dry AMD-like mouse model, elevated levels of oxidative stress markers, damaged mitochondria, accumulated lysosomal lipofuscin and extracellular drusen-like deposits were found.