E2F2 and neoplasm: Specifically, miR-150 negatively regulates forkhead box transcription factor (FOX)-P1, which inhibits the progression of lymphoid malignancies, while miR-31 targets E2F transcription factor 2 (E2F2) and class II PI3 kinases (PIK3C2A) and inhibits tumor cell proliferation in FL [9, 10].