In addition, since miR-424-5p regulates the proliferation and apoptosis of cancer cells in HCC [18], and it can also be used as a potential biomarker in the diagnosis of liver cancer [19], the relationship among MYLK-AS1, miR-424-5p, E2F7 and VEGFR-2 signaling pathway in HCC cells was studied. This evidence concerns the gene E2F7 and cancer.