CD8B and diffuse large B-cell lymphoma: To further demonstrate the specific role and target of KMT5A in DLBCL immunosuppression and CD73 regulation, we analyzed previously published H4K20me1 chromatin immunoprecipitation sequencing (ChIP-seq) data of DLBCL cell lines: OCI-LY1, OCI-LY3, OCI-LY7, and SU-DHL-6 (GSE96492, GSE96374, GSE96350, and GSE96226, respectively) [34], using the “chip seeker” package in the R program; a total of 864 genes were selected in the overlap of these four cell lines’ data (Fig. 7a).