Previous studies from our lab on breast cancer patients from same region have reported association of VEGF polymorphisms + 405C > G, + 936C > T, −2549 Insertion/Deletion, −152G/A, −116G/A, −165C/T and −141A/C with breast cancer risk but no association of VEGF −417C/T, −172C/A and −160C/T and HIF1α polymorphisms (g.C111A, g.C1772T and g.G1790A) with breast cancer risk [95–98]. The gene discussed is HIF1A; the disease is breast cancer.