ADIPOQ and gastroesophageal reflux disease: Consistent with this finding, serum adiponectin was found to be inversely associated with Barrett’s esophagus, particularly in men [181]; in patients with GERD, erosive esophagitis and Barrett’s esophagus were found to be associated with decreased adiponectin levels compared to those in patients without GERD [182]; and low serum adiponectin levels may be associated with an increased risk for erosive esophagitis [183].