ADIPOQ and fatty liver disease: Thus, after SVR, the decrease in adiponectin in G4 HCV-infected patients [81] may reflect the reversal of hepatic fibrosis and hypotriglyceridemia, whereas the increase in adiponectin in G3 HCV-infected patients [92] may indicate an improvement in hepatic steatosis, which is most evident in G3 HCV-infected patients [94].