MMP3 and gastric cancer: Slowed proliferation of AGS and SGC-7901 gastric cancer cells was also associated with downregulation of the proto-oncogene c-myc expression, cell cycle arrest at G0/G1 phase with the decreased expression of cyclin D1, whereas the antimetastatic potential of BBR on gastric cancer cell lines was manifested through downregulating MMP3 [51].