Studies have demonstrated that the combined treatment of TQ with 5-FU or CDDP significantly augments chemotherapeutic-induced antitumor effects on gastric cancer by enhancing the activation of the mitochondrial apoptotic pathway and some of the key proteins of this pathway, including Bax, Cyt c, AIF, cleaved caspase-9, and -3 [40,41]. Here, CASP9 is linked to gastric cancer.