Overexpression in multiple epithelial tumors, expression all over the surface of a tumor cell due to loss of apicobasal polarity in cancer cells, thus making it accessible to antibodies and tumor-specific aberrant glycosylation with truncated carbohydrate antigens Tn and TF in the VNTR region are features that make MUC1 an attractive target for immunotherapy [37]. The gene discussed is TF; the disease is neoplasm.