Analyzing the annotated targets of the identified compounds revealed that several pathways, including ROS (reactive oxygen species) modulation, fatty acid biosynthesis regulation, MDM2-p53 signaling, receptor tyrosine kinases, NAMPT (nicotinamide phosphoribosyltransferase), ubiquitin-proteasome and, particularly, PI3K-AKT1-mTOR and epigenetic regulators, are enriched (Table S2), suggesting that these signaling cascades may be involved in ferroptosis deregulation in cancer. The gene discussed is MTOR; the disease is cancer.