The administration of DMBA increased the levels of AST and ALT in rats, which suggests DMBA-induced hepatic damage [29,30], which agrees well with the findings of the present study: induction of breast cancer by DMBA resulted in raised levels of ALT, AST, and BUN compared with the control group because of the hazardous effects of DMBA on the hepatic cells and kidneys. This evidence concerns the gene GPT and breast carcinoma.