In addition, Slc7a5 is essential for T cell differentiation and clonal expansion (Marchingo et al., 2020), correlated to negative outcomes and growth of many proliferating tumor cell types (Salisbury and Arthur, 2018), and causes embryonic lethality in Slc7a5 knockout mice (Poncet et al., 2020). The gene discussed is SLC7A5; the disease is neoplasm.