SLC7A5 and epilepsy: Strikingly, certain epilepsy-linked mutations of Kv1.2 are hypersensitive to Slc7a5-mediated modulation, leading to extraordinarily large (sometimes >100 mV) gating shifts when co-expressed with Slc7a5 (Baronas et al., 2018; Masnada et al., 2017; EuroEPINOMICS RES consortium et al., 2015).