Thirty psoriasis patients were subjectedto a ketogenic nutritional regimen and monitored by evaluating (i)the clinical symptoms, (ii) the blood biochemical parameters, includingIL-2, IL-1β, TNF-α, IFN-γ, and IL-4, and (iii) themetabolomic profile, as derived from 1H NMR analysis. The gene discussed is TNF; the disease is psoriasis.