HDAC9 and cancer: In addition to its anti-cancer effect via transcription-dependent mechanisms, HDAC inhibition impacts cell proliferation, survival, and angiogenesis via modulation of molecular chaperones, signal transduction proteins, cytoskeletal proteins, cytoplasmic-nuclear transport, and inhibition of hypoxia inducible factors and vascular endothelial growth factor (Glozak et al., 2005; Liang et al., 2006; Witta, 2012).