There was no significant difference in age, sex, BMI, hepatitis B virus infection, serum AFP, alanine aminotransferase (ALT), leukocyte count, lymphocyte count, monocyte count, platelet count, and the size, number, differentiation, vascular invasion, AJCC8th, and BCLC stage of tumors between the two groups. The gene discussed is AFP; the disease is hepatitis B virus infection.