Treatment of HCT116 colon cancer cells with 70 μg/ml of C. orbiculata extract resulted in an increase in the co-precipitation of hnRNPA2B1 with BCL2L1 (Figure 7A), BCL2 (Figure 7B), MDM2 (Figure 7C), cMYC (Figure 7D), CD44 (Figure 7E), CDK6 (Figure 7F), and cJUN (Figure 7G) mRNA. This evidence concerns the gene MDM2 and colonic neoplasm.