The degree of inflammatory burden of IBD patients is influenced by the dysfunction of susceptibility genes for IBD, such as autophagy-related 16 like 1 (ATG16L1), chromosome 1 open reading frame 106 (C1orf106), oncostatin M (OSM), and oncostatin M receptor (OSMR) [17–19]. Here, ATG16L1 is linked to inflammatory bowel disease.