IL6 and liver cancer: Additionally, carvacrol has demonstrated cytotoxicity against human cervical cancer cells HeLa [14], as well as antiproliferative and apoptotic on human liver cancer cells HepG-2 [15], cytotoxicity in AGS human gastric adenocarcinoma cells [15], liver cancer in rats [16], apoptosis in human oral squamous cell carcinoma (OSCC), and antiproliferative in N2a neuroblastoma cells; in PC-3 prostate, cancer cells reduced the IL-6 protein levels, pSTAT3, pERK1/2, and pAKT signaling proteins.