Additionally, our group also found that the upregulated serum GITRL has a positive correlation with the percentage of Th17 cells in Hashimoto’s thyroiditis patients, and the increased GITRL may impair the balance of Th17/Treg, thus contributing to the pathogenesis of Hashimoto’s thyroiditis (60). Here, TNFSF18 is linked to Hashimoto thyroiditis.