CRP and bacterial infectious disease: Data from our group showed, that in neonates suffering from bacterial infection GR-MDSC may dramatically expand, even from the elevated level seen in healthy neonates (50), and that GR-MDSC levels correlated with inflammatory markers such as C-reactive protein (CRP), demonstrating the influence of an inflammatory environment of MDSC at least on their expansion, as seen in adult patients [reviewed in: (55)].