IL-34-mediated growth of myelogenous leukemia cell line M-NFS-60 can be inhibited by three different IL-34 neutralizing antibodies, which were further used in this study and showed similar potencies [mouse monoclonal v1.1 (25): IC50 0.43 nM, rat monoclonal MAB5195: IC50 0.53 nM, sheep polyclonal AF5195: IC50 2.05 Nm] (Figure 1B), indicating that CSF1R-dependent signaling can be modulated by IL-34 inhibition. Here, CSF1R is linked to myeloid leukemia.