Additionally, when the plasma of atherosclerotic mice was analyzed for the presence of antibodies against oxLDL, in mice transplanted with SIRPαΔCYT cells elevated levels of T15/E06 IgM (Figure 5C), an oxLDL neutralizing antibody, being particularly critical in the protection against atherosclerosis, were found. The gene discussed is CD40LG; the disease is atherosclerosis.