Apart from the features commonly affected in MS serum and CSF, twelve features (IL-1β, IL-2, IL-7, IL-9, IL-10, IL- 12(p70), IL-16, CCL3, CCL4, GM-CSF, PDGF, and TRAIL) found exclusively altered in CSF in MS as compared to non-MS. Here, CCL4 is linked to myeloid sarcoma.