However, more cytokines, total of twenty (IL-1β, IL-4, IL-5, IL12-p40, IL-18, CCL2, CCL3, CCL11, CCL27, CXCL1, CXCL9, FGF-basic, IFN-γ, M-CSF, β-NGF, PDGF-bb, SCF, SCGF-b, SDF-1a, and VEGF), were affected in serum when compared to CSF in MS. This evidence concerns the gene IL18 and myeloid sarcoma.