HDAC6-selective inhibitors, tubastatin A, CAY10603, and ACY1215 inhibited cell proliferation and induced apoptosis of U-87MG, U251, and A172 cells by inhibiting HDAC6 34 and HDAC inhibitors sensitized glioblastoma cells to TMZ and radiotherapy 34, 39-43. The gene discussed is HDAC9; the disease is glioblastoma.