ADAMTS13 and Genetic thrombotic microangiopathy: Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia and thrombocytopenia developed due to deficiency of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) [1].