On the contrary, other studies revealed that miRNA‐150 may act as a tumor‐suppressor miRNA, where it was found to be down‐regulated in esophageal squamous cell carcinoma,28 and it inhibited the growth and malignant behavior of pancreatic cancer cells by targeting mucin 4 (MUC4).27 This evidence concerns the gene MUC4 and esophageal squamous cell carcinoma.