BIM, which acts as a tumour suppressor in lymphomagenesis, is epigenetically silenced through the following steps: MeCP2 is recruited to methylate CpGs and then binds the SIN3a/histone deacetylase 1/2 (HDAC1/2) corepressor complex to deacetylate histone tails in anaplastic large-cell lymphoma, according to Rocco Piazza’s report [41]. This evidence concerns the gene HDAC1 and anaplastic large cell lymphoma.