METTL3 and metabolic syndrome: To further explore the underlying mechanisms of Mettl3 depletion in protecting liver from metabolic syndrome induced by HFD, we analyzed RNA-seq and miCLIP-seq data generated from livers of Mettl3Ctrl and Mettl3cKO mice after 20 weeks of HFD (termed as Mettl3Ctrl(HFD) and Mettl3cKO(HFD), respectively).