Similarly, when we fit a logistic regression predicting the infection status of each cell using macrophage score, smoothed CD14 and CD16 expression values, and a CD14xCD16 interaction term (STAR Methods), both the CD14xCD16 interaction term (which is highest in DPs) and macrophage score were positively associated with infection, while the CD14 and CD16 terms were negatively associated (p < 0.01 for all coefficients). The gene discussed is FCGR3A; the disease is infection.