According to previous studies, heterozygous COL4A3/COL4A4 mutations can lead to AS, thin basement membrane disease, segmental GBM thin, as well as FSGS (Lin et al., 2014; Lu et al., 2017; Malone et al., 2014; Storey et al., 2013; Zhu et al., 2018). This evidence concerns the gene COL4A3 and glycogen storage disease VI.