Although LPS stimulation induced IL‐6 secretion in all cell cultures (Figure 2), activated HA‐FLS (Figure 2A) did not release any detectable amount of IL‐1α in cell culture supernatants in a similar manner than RA‐FLS (Figure 2C), whereas non‐HA‐FLS (Figure 2B), HR‐FLS (Figure 2D) and THP‐1 cell lines (Figure 2E) did release significant detectable amounts of IL‐1α. This evidence concerns the gene IL1A and rheumatoid arthritis.