As surrogate parameters for PSMA expression, we compared the change in SUVmax, SUVmean, PSMA-derived tumor volume (PSMA-TV) and total lesion PSMA (TL-PSMA) [18], and the miPSMA score [19] under ADT was compared for the primary tumor as well as the lymphatic and bone metastases within each other and the respective PSA values. Here, KLK3 is linked to neoplasm.