Given that chmp7+/− fish possess similar reductions in chmp7 mRNA levels to individuals homozygous for the CHMP7 ADHD risk allele, we examined if reduced chmp7 mRNA levels lead to a hyperactivity phenotype at embryonic (6 dpf), juvenile (42 dpf), and adult (84 dpf) stages. The gene discussed is CHMP7; the disease is attention deficit-hyperactivity disorder.