Another up-regulated lncRNA, PTCSC3, may also regulate the thyroid cancer tumor microenvironment via activating the Wnt signaling pathway [55].The up-regulation of miR-574-5p and miR-195 has been discussed in Section 2.1 to induce proliferation, EMT, invasion and migration via activating the Wnt pathway in thyroid cancer. The gene discussed is PTCSC3; the disease is thyroid cancer.